Listar por autor "Marsal, Sara"

Mostrando ítems 1-9 de 9

    • A combined transcriptomic and genomic analysis identifies a gene signature associated with the response to anti-TNF therapy in rheumatoid arthritis 

      Aterido, Adriá; Cañete, Juan D.; Tornero, Jesús; Blanco García, Francisco J; Fernández-Gutiérrez, Benjamín; Pérez, Carolina; Alperi-López, Mercedes; Olivé, Alex; Corominas, Héctor; Martínez-Taboada, Víctor; González, Isidoro; Fernández-Nebro, Antonio; Erra, Alba; López-Lasanta, María; López-Corbeto, Mireia; Palau, Núria; Juliá, Antonio; Marsal, Sara (Frontiers, 2019-07-02)
      [Abstract] Background: Rheumatoid arthritis (RA) is the most frequent autoimmune disease involving the joints. Although anti-TNF therapies have proven effective in the management of RA, approximately one third of patients ...

    • A functional variant of TLR10 modifies the activity of NFkB and may help predict a worse prognosis in patients with rheumatoid arthritis 

      Torices, Silvia; Juliá, Antonio; Muñoz, Pedro; Varela, Ignacio; Balsa, Alejandro; Marsal, Sara; Fernández-Nebro, Antonio; Blanco García, Francisco J; López-Hoyos, Marcos; Martínez-Taboada, Víctor; Fernández-Luna, José L. (Springer, 2016-10-04)
      [Abstract] Background. Toll-like receptor (TLR) family members are key players in inflammation. TLR10 has been poorly studied in chronic inflammatory disorders, and its clinical relevance in rheumatoid arthritis (RA) is ...

    • Blood RNA sequencing reveals immunological processes associated with the response to abatacept in rheumatoid arthritis. 

      Julià, Antonio; López Lasanta, María; Gómez, Antonio; Sanmartí, Raimon; Marras, Carlos; Pina Salvador, José Manuel; Romero Yuste, Susana; Veiga Cabello, Raúl María; Navarro, Pilar; Moragues Pastor, Carme; Martínez Pardo, Silvia; De-Toro, Javier; Sánchez, Amalia; Cerda, Dacia; Prada, Alejandro; Erra, Alba; Monfort, Jordi; Urruticoechea-Arana, Ana; Palau, Núria; Lastra, Raquel M.; Tortosa, Raúl; Pluma Sanjurjo, Andrea; Marsal, Sara (BMJ Journals, 2019-05-27)

    • Cardiovascular disease in immune-mediated inflammatory diseases: a cross-sectional analysis of 6 cohorts 

      Fernández-Gutiérrez, Benjamín; Perrotti, Pedro P.; Gisbert, Javier P.; Doménech, Eugeni; Fernández-Nebro, Antonio; Cañete, Juan D.; Ferrándiz, Carlos; Tornero, Jesús; García-Sánchez, Valle; Panés, Julián; Fonseca, Eduardo; Blanco García, Francisco J; Rodríguez-Moreno, Jesús; Carreira, Patricia; Juliá, Antonio; Marsal, Sara; Rodríguez-Rodríguez, Luis (Wolters Kluwer, 2017-06)
      [Abstract] To analyze in several immune-mediated inflammatory diseases (IMIDs) the influence of demographic and clinical-related variables on the prevalence of cardiovascular disease (CVD), and compare their standardized ...

    • Interactions between rheumatoid arthritis antibodies are associated with the response to anti-tumor necrosis factor therapy 

      Juliá, Antonio; López-Lasanta, María; Blanco García, Francisco J; Gómez, Antonio; Haro, Isabel; juan Más, Antonio; Erra, Alba; García-Vivar, María L.; Monfort, Jordi; Sánchez-Fernández, Simón; González, Isidoro; Alperi-López, Mercedes; Castellanos-Moreira, Raúl; Fernández-Nebro, Antonio; Díaz-Torné, César; Lastra, Raquel M.; Lladós, Jordi; Palau, Núria; Sanmartí, Raimon; Marsal, Sara (Springer, 2021-04-21)
      [Abstract] Background. Blocking of the Tumor Necrosis Factor (TNF) activity is a successful therapeutic approach for 50–60% of rheumatoid arthritis (RA) patients. However, there are yet no biomarkers to stratify patients ...

    • Longitudinal analysis of blood DNA methylation identifies mechanisms of response to tumor necrosis factor inhibitor therapy in rheumatoid arthritis 

      Juliá, Antonio; Gómez, Antonio; López-Lasanta, María; Blanco García, Francisco J; Erra, Alba; Fernández-Nebro, Antonio; Juan Mas, Antonio; Pérez-García, Carolina; García Vivar, María Luz; Sánchez-Fernández, Simón; Alperi-López, Mercedes; Sanmartí, Raimon; Ortiz, Ana María; Marras Fernández-Cid, Carlos; Díaz-Torné, César; Moreno, Estefanía; Li, Tianlu; Martínez-Mateu, Sergio H.; Absher, Devin M.; Myers, Richard M.; Tornero Molina, Jesús; Marsal, Sara (Elsevier, 2022-05-13)
      [Abstract] Background: Rheumatoid arthritis (RA) is a chronic, immune-mediated inflammatory disease of the joints that has been associated with variation in the peripheral blood methylome. In this study, we aim to identify ...

    • Seven-chain adaptive immune receptor repertoire analysis in rheumatoid arthritis reveals novel features associated with disease and clinically relevant phenotypes 

      Aterido, Adriá; López-Lasanta, María; Blanco García, Francico J; Juan-Mas, Antonio; García-Vivar, María Luz; Erra, Alba; Pérez-García, Carolina; Sánchez-Fernández, Simón Ángel; Sanmartí, Raimón; Fernández-Nebro, Antonio; Alperi-López, Mercedes; Tornero, Jesús; Ortiz, Ana María; Marras Fernández-Cid, Carlos; Palau, Núria; Pan, Wenjing; Byrne-Steele, Miranda; Starenki, Dmytro; Weber, Daniel; Rodríguez-Nunez, Iván; Han, Jian; Myers, Richard M.; Marsal, Sara; Juliá, Antonio (Springer Nature, 2024-03-11)

    • Urine metabolome profiling of immune-mediated inflammatory diseases 

      Arnald Alonso, Antonio Juliá; Vinaixa, María; Domènech, Eugeni; Fernández-Nebro, Antonio; Cañete, Juan D.; Ferrándiz, Carlos; Tornero, Jesús; Gisbert; Nos, PIlar; Gutiérrez Casbas, Ana; Puig, Lluís; González-Álvaro, Isidoro; Pinto-Tasende, José A.; Blanco, Ricardo; Rodríguez, Miguel A.; Beltrán, Antoni; Correig, Xavier; Marsal, Sara (Springer, 2016-09-08)
      [Abstract] Background, Immune-mediated inflammatory diseases (IMIDs) are a group of complex and prevalent diseases where disease diagnostic and activity monitoring is highly challenging. The determination of the metabolite ...

    • Variation at interleukin-6 receptor gene is associated to joint damage in rheumatoid arthritis 

      López-Lasanta, María; Juliá, Antonio; Maymó, Joan; Fernández-Gutiérrez, Benjamín; Ureña-Garnica, Inmaculada; Blanco García, Francisco J; Cañete, Juan D.; Alperi-López, Mercedes; Olivé, Alex; Corominas, Héctor; Tornero, Jesús; Erra, Alba; Almirall, Miriam; Palau, Nuria; Ortiz, Ana; Ávila, Gabriela; Rodríguez-Rodríguez, Luis; Alonso, Arnald; Tortosa, Raül; González-Álvaro, Isidoro; Marsal, Sara (BMC, 2015-09-04)
      [Abstract] Introduction. Interleukin-6 (IL-6) cytokine signaling is key in Rheumatoid Arthritis (RA) pathophysiology. Blocking IL-6 receptor (IL6R) has proven to be a highly effective treatment to prevent joint damage. ...